WASHINGTON — US health officials are investigating whether electronic cigarettes may trigger seizures in some people who use the nicotine-vaping devices.
The Food and Drug Administration said Wednesday that it has reviewed 35 reports of seizures among e-cigarettes users, mainly in young people. Regulators stressed it’s not yet clear whether vaping is responsible. But they said they’re concerned and encouraged the public to report information about the issue.
These cases warrant ‘‘investigation into whether there is in fact a connection,’’ FDA Commissioner Scott Gottlieb said in a statement.
Cases go back to 2010 and were reported to the FDA or poison control centers around the country. Regulators said they detected an uptick in reports beginning mid-2018.
Most e-cigarettes heat a flavored nicotine solution into an inhalable vapor. The battery-powered devices have grown into a multibillion dollar industry though there are few standards, including how much nicotine they deliver. Additionally, many refillable e-cigarettes can be used with nicotine formulas of varying strength.
Nicotine poisoning can cause seizures, convulsions, vomiting, and brain injury. The FDA has previously warned of potentially fatal nicotine poisoning in infants and children who accidentally swallowed nicotine solutions.
Seizures usually last a few seconds or minutes and rarely cause permanent injury. But they can be a sign of underlying neurological disorders that need medical attention.
Laboratory and animal studies have found a link between nicotine and hyperactivity in the brain. What needs further study is what type of e-cigarette could deliver levels of nicotine capable of causing seizures, said Maciej Goniewicz, a toxicologist at Roswell Park Comprehensive Cancer Center in Buffalo.