Raffles hotel coming to Boston via new Back Bay tower

The chain where the Singapore Sling was invented will build in Back Bay.

Drugs were packed at a Takeda pharmaceutical company facility in Oranienburg, Germany.

Shire takeover may take months to finish

For Shire PLC’s more than 3,000 employees in Massachusetts, now comes the waiting.

Automatic for the people: Logan to study if a train (or monorail) should replace shuttles at the airport

Officials will spend $15 million to design and study the feasibility of a “people mover” like the trains or monorails used at other busy airports.

Lowell, MA -- 2/19/2018 - Phil Caminti and his wife, Ali Mercier sit with their four week old baby, Quinn, and their dog, Ada, inside the new home they just purchased in Lowell. (Jessica Rinaldi/Globe Staff) Topic: 11zohousesearch Reporter:

Condos more costly than houses in Massachusetts

The median price of a condo sold in March was $20,000 higher than for single-family homes.

Latest Business headlines

FEMA may let people rebuild on same flood-prone sites where they got post-disaster buyouts

FEMA proposes letting homeowners sell their damaged homes to the government but retain ownership of the property underneath them.

Facebook reaps soaring profits amid turbulent times

‘‘Despite facing important challenges, our community and business are off to a strong start in 2018,’’ Mark Zuckerberg, Facebook CEO, said in a statement.

Comcast starts bidding war with 21st Century Fox for Sky

Comcast formally unveiled a $30.7 billion takeover bid for Sky on Wednesday, putting the U.S. cable giant squarely in a takeover battle with Rupert Murdoch’s 21st Century Fox for control over the British satellite broadcaster.

Twitter is profitable again in 1Q, Wall Street not impressed

Twitter has remained largely outside of the crosshairs of Congress over the privacy issues that have tripped up Facebook, but it continues to face its own, unique challenges.

Medicaid needs to change, head of program says in Boston, and that includes spending caps

Seema Verma expressed support for an idea backed by many conservatives: implementing limits on Medicaid spending.

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Sean P. Murphy is the Globe’s consumer columnist, and he’s here to take your queries.

Globe Magazine

Special section | Game Changers

//c.o0bg.com/rf/image_90x90/Boston/2011-2020/2017/05/11/BostonGlobe.com/Business/Images/gamechangershoriz-6383.jpg 51 bright ideas and breakthroughs for 2017

In a revolutionary place like Boston, innovators and innovations are as common as bad drivers. See who made our annual list.

STAT

//c.o0bg.com/rf/image_90x90/Boston/2011-2020/2018/04/25/BostonGlobe.com/National/Images/Veale.jpg ‘Regifting’ transplanted kidneys could ease the organ shortage

A surgeon has transplanted three “regifted” kidneys from previous transplant recipients who died — breaking an unspoken taboo.

More Business headlines

Business agenda

Entrepreneurship, networking, and more.

Stocks close mixed; Dow industrials end a losing streak

A late round of buying erased early losses on Wall Street, leaving major indexes mixed at the close of trading.

The Wynn Boston Harbor Resort Casino is under construction in Everett.

Shirley Leung

Will Wynn blink first in its showdown over the Everett casino?

A high-stakes game of chicken is being played out in Everett, and the newly expanded board of Wynn Resorts may be the key to the fate of the $2.5 billion project.

Subway sandwich chain plans 500 US store closings amid global growth

Last year, more than 800 stores went dark, with the total US count dropping to 25,908.

Gaia’s all-sky view of our Milky Way Galaxy and neighboring galaxies.

Scientists release the most detailed star chart of the Milky Way yet

The European Space Agency released the most accurate census yet of stars in the Milky Way and neighboring galaxies.

 Twitter swung to a profit during the first quarter of the year.

Twitter is profitable again in 1st quarter, grows overseas

Twitter, driven by strong growth overseas, swung to a profit during the first quarter of the year, its second profitable quarter ever after a strong finish last year.

The sign outside Sky Plc’s headquarters in Isleworth, West London.

Sky reconsiders Fox offer after Comcast bid

The London-based pay TV operator withdrew its recommendation to shareholders on the Fox deal just moments after Comcast placed a better offer on the table.

Loot boxes can be earned by playing video games or can be bought with money and are a substantial revenue stream for the video game industry. But some lawmakers say they constitute gambling and should be regulated.

Video game ‘loot boxes’ eyed by states as akin to gambling

Today, many video games let players at home spend a dollar — or much more — to open digital “loot boxes” that offer features like new character outfits and powerful weapons.

Stock market volatility is back, and it is leaving older investors anxious about their retirement plans

Many retirees, and people nearing retirement, are well aware of the market’s recent volatility. But financial advisers warn against worrying about every up and down.

A seemingly innocuous comment from a Caterpillar executive prompted the markets to drop more than 2 percent Tuesday.

Stocks slide after a comment from a Caterpillar executive rattles the market

Brad Halverson said Caterpillar’s first-quarter profit ‘‘will be the high-water mark for the year’’ because of increased investment later in 2018. Traders freaked out.

The Food and Drug Administration said it had issued warning letters to several dozen retailers and demanded that Juul Labs submit company documents with health and marketing information.

US agency cracks down on Juul e-cigarette popular in schools

Federal health officials Tuesday announced a nationwide crackdown on underage use of a popular e-cigarette brand.

Facebook has not changed its Community Standards, but rather has just made them public.

Facebook rules at a glance: What’s banned, exactly?

Facebook has revealed for the first time what is banned on its service in a new Community Standards document released on Tuesday.

Kristen Mutacio will teach the basics of HTML and CSS coding on Thursday.

Business agenda

Learn website building, visit a mixer for women in business, and other events and things to know.

Harvard University’s endowment is about $37.1 billion.

Harvard land ownership in Brazil in dispute

The prosecutor’s office in the state of Bahia said it’s reviewing allegations that a company linked to Harvard’s endowment isn’t the rightful owner of land in the region, and it’s determining whether to sue to reclaim the titles.

The burgers feature the same blend of Angus brisket, chuck, and short rib used in the restaurants, a recipe created by Paul Wahlberg.

Wahlburgers looks to expand into retail business

The Wahlberg brothers have found a new place to grow their restaurant empire: the supermarket aisle.

Traders worked the floor of the New York Stock Exchange.

Evan Horowitz | Quick Study

Stocks are plunging. Blame bonds

The yield on the 10-year Treasury bond touched 3 percent on Tuesday. The Dow closed down more than 424 points. There is a connection.

The only time a Spyce Food employee touches food in the restaurant is to hand the grain bowl off the customer.

The robots are coming — to cook you a healthy grain bowl

The Spyce Food Co. is getting ready to open a restaurant with a mechanized kitchen in downtown Boston.

State Street Corp.’s headquarters, One Financial Center, at 1 Lincoln St. in Boston.

Is State Street leaving its HQ tower?

The financial services firm’s lease at One Financial Center ends in 2023, and it’s examining its options for downtown office space.

Dr. Leslie Gordon with her son, Sam Berns, who died in 2014.

A pediatric researcher whose son died of progeria sees promise in new treatment

Dr. Leslie Gordon, whose son Sam Berns died at 17, hasn’t found a cure — but she’s convinced that she and fellow researchers have hit on a promising treatment.

The Takeda Pharmaceutical plant in Osaka, Japan.

Shire accepts a $64b takeover offer from Takeda, will seek shareholders’ backing

Shire is headquartered in Ireland but has most of its operations in Lexington.

GM says more than 7 million owners of Chevrolet, Buick, GMC and Cadillac vehicles are eligible for Amazon’s new Amazon Key In-car delivery service.

Amazon begins delivery to vehicles

The company said it has started delivering packages in 37 cities to Prime members who own newer General Motors or Volvo vehicles with remote assistance systems.

Boston-based Vertex has faced challenges from governments in several countries about its drug prices.

STAT

Vertex to meet with UK regulators over disputed medicine

Two UK health ministers are calling on Vertex Pharmaceuticals to provide an “urgent resolution” to negotiations over access to its cystic fibrosis drug.

Even with Kyrie Irving sidelined for the playoffs, more than 97 percent of Celtics season ticket holders have renewed for 2018-19.

BOLD TYPES

The renewal rate for Celts’ season tickets: It’s nearly perfect

The team can already chalk up this season as a financial success.

Even in the sharp-elbowed world of Boston politics, public attacks by an out-of-town company like Airbnb on a city councilor are rare.

The war over Airbnb regulations in Boston keeps escalating

The debate in Boston had been largely civil — at least compared to lawsuits and loud protests in cities such as New York and Los Angeles — until last week.

Homes near ocean risk losing value, even in a hot market

As the spring real estate season blooms, the memory of the winter’s inundating storms hangs over water-view properties that otherwise would command premium prices.

NAFTA ministers set to meet again amid intensified push for deal

‘‘We have had some very energetic and productive conversations,’’ said Chrystia Freeland, Canada’s minister for foreign affairs.

Suspicious or fraudulent reviews are crowding out authentic ones in some categories, a Post study found.

How merchants quietly use Facebook to flood Amazon with fake reviews

Suspicious or fraudulent reviews are crowding out authentic ones in some categories, a Post study found.

Vanguard aims to bring low-cost investing to China as the country eases its restrictions

Vanguard Group revolutionized the US investment industry by offering low-cost funds. Now it wants to do something similar in China.

Sears’ biggest shareholder offers to buy Kenmore brand

Sears’ biggest shareholder has suggested the company sell its well-known Kenmore brand and some real estate holdings, offering itself as a potential buyer.

Stocks wobble as bond yields set four-year highs

US stocks couldn’t hang on to an early gain and finished mostly lower Monday as technology companies slipped.

Russian billionaire Oleg Deripaska, who heads aluminium producer Rusal, has been targeted as part of a US sanctions package that hit dozens of Russian tycoons, companies, and key allies of President Vladimir Putin.

US softens stance on Rusal sanctions; aluminum plunges

For the first time, the US Treasury discussed a path for lifting the sanctions on Rusal, saying it would provide relief if Oleg Deripaska relinquished control.

Regular gasoline is selling for an average price of $2.74 a gallon in Massachusetts, up 17 cents in the past month.

Evan Horowitz | Quick Study

Gas prices are up 15 percent — and they’re probably going higher

And the increases will wipe out any gains lower-income Americans got from the recently passed tax cuts, analysts say.

Business agenda

Networking, a panel discussion, and other events and things to know.

Eddie Lampert’s hedge fund, Sears’ biggest shareholder, has asked the struggling retailer to sell the Kenmore brand and its home improvement business.

Firm offers to buy Kenmore from Sears

The private equity firm that is Sears’ biggest shareholder has asked the struggling retailer to sell the Kenmore brand and its home improvement business.

Elijah Botkin has refused to pay a renewal fee that appears to be illegal in the state.

Sean P. Murphy | The Fine Print

Watch out for fees when renting an apartment

Elijah Botkin did something few tenants would dare to do: He refused to pay a surprise charge sprung on him by his landlord’s agent.

Alexander Kogan says he was upfront about how the information would be used and that he “never heard a word” of objection from Facebook.

Cambridge Analytica contractor defends role in data gathering

Alexander Kogan said he was upfront about how the data would be used and that Facebook never objected.

STAT

Amazon and its partners want to upend health care services

The direct primary care business is growing.

A combination of lousy weather, international demand, and iced-over Canadian fisheries has created a lobster shortage.

A $49 lobster roll? A recent shortage has lobster prices soaring.

The costs of lobster dishes on Boston restaurant menus have been off the charts as chefs look to claw back some of the margins.

The week ahead in business

An intro to product management, the future of food products, and other events and things to know.

Jeff Mcpherson, an applicant for an apprentice-ship program, worked with other IBEW Local 103 laborers at J&M Brown Company’s prefab shop.

White-dominated construction unions want more diversity

IBEW Local 103’s campaign attracted a record number of female and minority applicants, in line with a national push by building trades.

Harvard undergrads will launch a cryptocurrency fund, starting at $1m

Bushra Hamid, 19, has teamed up with three schoolmates to form Plympton Capital, which has already raised $700,000.

Tech Lab by Hiawatha Bray

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Bray writes about technology for the Business section. His Tech Lab column appears on Thursdays.

Shirley Leung

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Leung writes a business column every Wednesday and Friday. Previously she served six years as the business editor overseeing daily and Sunday coverage.